Hideo Akiyama Selected Research

Hypoxia (Hypoxemia)

10/2018	Retinal Detachment-Induced Müller Glial Cell Swelling Activates TRPV4 Ion Channels and Triggers Photoreceptor Death at Body Temperature.
10/2007	The SDF-1/CXCR4 ligand/receptor pair is an important contributor to several types of ocular neovascularization.
2/2006	Triamcinolone acetonide suppresses interleukin-1 beta-mediated increase in vascular endothelial growth factor expression in cultured rat Müller cells.
4/2005	Visible light exposure induces VEGF gene expression through activation of retinoic acid receptor-alpha in retinoblastoma Y79 cells.
5/2004	Inhibition of ocular angiogenesis by an adenovirus carrying the human von Hippel-Lindau tumor-suppressor gene in vivo.
7/2002	Endothelial PAS domain protein 1 (EPAS1) induces adrenomedullin gene expression in cardiac myocytes: role of EPAS1 in an inflammatory response in cardiac myocytes.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Hideo Akiyama Research Topics

Disease

14	Macular Degeneration (Age-Related Maculopathy) 01/2024 - 07/2006
12	Choroidal Neovascularization 03/2023 - 09/2005
12	Neoplasms (Cancer) 01/2023 - 02/2002
8	Inflammation (Inflammations) 01/2024 - 01/2014
8	Polypoidal Choroidal Vasculopathy 01/2024 - 10/2017
6	Hypoxia (Hypoxemia) 10/2018 - 07/2002
5	Keratitis 06/2023 - 02/2019
4	Retinal Neovascularization 01/2024 - 12/2005
4	Central Serous Chorioretinopathy 11/2023 - 01/2018
4	Retinal Detachment (Retinal Detachments) 01/2019 - 07/2005
4	Dry Eye Syndromes (Dry Eye Syndrome) 01/2014 - 01/2012
4	Rupture 01/2009 - 09/2005
3	Atrophy 01/2023 - 01/2018
3	Macular Edema 02/2021 - 02/2006
2	Glaucoma 05/2024 - 02/2023
2	Infections 06/2023 - 11/2015
2	Hypothyroidism 10/2022 - 01/2022
2	Pathologic Constriction (Stenosis) 08/2022 - 01/2021
2	Disease Progression 01/2022 - 01/2021
2	Cicatrix (Scar) 07/2021 - 05/2006
2	Papilledema 02/2021 - 07/2008
2	Melanoma (Melanoma, Malignant) 01/2019 - 06/2014
2	Endophthalmitis (Ophthalmia) 06/2018 - 09/2017
2	Lagophthalmos 01/2014 - 01/2013
2	Gastritis 01/2014 - 01/2012
2	Stomach Ulcer (Gastric Ulcer) 01/2014 - 01/2012
2	Renal Cell Carcinoma (Grawitz Tumor) 12/2008 - 05/2004
2	Retinal Vein Occlusion 07/2008 - 05/2004
2	Retinoblastoma (Glioblastoma, Retinal) 04/2005 - 05/2002
1	Wounds and Injuries (Trauma) 02/2023
1	Mydriasis 02/2023
1	Ulcer 01/2023
1	Cardiac Arrhythmias (Arrythmia) 08/2022
1	Thromboembolism 08/2022
1	Adenocarcinoma 01/2022
1	Glucose Intolerance 01/2022
1	Epiretinal Membrane (Epiretinal Membranes) 02/2021
1	Ocular Paraneoplastic Syndromes 01/2021
1	Herpetic Keratitis 06/2019

Drug/Important Bio-Agent (IBA)

10	afliberceptIBA 01/2023 - 01/2017
10	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 02/2021 - 02/2002
9	Proteins (Proteins, Gene)FDA Link 01/2023 - 07/2002
9	Retinaldehyde (Retinal)IBA 07/2018 - 09/2006
7	brolucizumabIBA 01/2024 - 01/2021
5	Voriconazole (Vfend)FDA LinkGeneric 06/2023 - 02/2018
4	1-phenyl-3,3-dimethyltriazene (PDT)IBA 11/2023 - 01/2021
4	SteroidsIBA 01/2023 - 01/2021
4	Messenger RNA (mRNA)IBA 11/2015 - 07/2002
4	rebamipideIBA 01/2014 - 01/2012
3	Fluorescein (Funduscein)FDA LinkGeneric 01/2024 - 09/2005
3	RNA (Ribonucleic Acid)IBA 01/2022 - 02/2006
3	DNA (Deoxyribonucleic Acid)IBA 01/2017 - 01/2007
3	MucinsIBA 01/2014 - 01/2012
3	Biomarkers (Surrogate Marker)IBA 01/2012 - 05/2008
2	Nylons (Nylon)IBA 05/2024 - 02/2023
2	faricimabIBA 01/2024 - 10/2023
2	Ribosomal DNA (rDNA)IBA 06/2023 - 06/2019
2	IpilimumabIBA 01/2023 - 01/2019
2	CytokinesIBA 10/2018 - 04/2005
2	Triamcinolone Acetonide (Azmacort)FDA LinkGeneric 02/2018 - 02/2006
2	MicroRNAs (MicroRNA)IBA 04/2014 - 03/2011
2	4- chloro- 3- (5- methyl- 3- ((4- (2- pyrrolidin- 1- ylethoxy)phenyl)amino)- 1,2,4- benzotriazin- 7- yl)phenolIBA 07/2008 - 03/2008
2	CGC-11144IBA 11/2006 - 09/2005
2	PolyaminesIBA 11/2006 - 09/2005
2	Interleukin-1beta (Interleukin 1 beta)IBA 02/2006 - 07/2002
2	Tretinoin (Retinoic Acid)FDA LinkGeneric 05/2002 - 02/2002
1	Thyrotropin-Releasing Hormone (Protirelin)FDA Link 10/2022
1	OpsinsIBA 10/2022
1	ParaffinIBA 01/2022
1	Formaldehyde (Formol)FDA Link 01/2022
1	Glucose (Dextrose)FDA LinkGeneric 01/2022
1	Phenobarbital (Luminal)FDA Link 01/2022
1	Thyroid HormonesIBA 01/2022
1	Antiviral Agents (Antivirals)IBA 07/2021
1	AutoantibodiesIBA 01/2021
1	Transient Receptor Potential ChannelsIBA 01/2021
1	Miconazole (Monistat)FDA LinkGeneric 06/2019
1	Betamethasone (Celestone)FDA Link 06/2019
1	luliconazoleIBA 02/2019
1	Natamycin (Pimaricin)FDA Link 02/2019
1	N-acetyltalosaminuronic acid (NAT)IBA 02/2019
1	Dacarbazine (DIC)FDA LinkGeneric 01/2019
1	Immune Checkpoint InhibitorsIBA 01/2019
1	NivolumabIBA 01/2019
1	Interferon-betaIBA 01/2019

Therapy/Procedure

8	Therapeutics 01/2024 - 06/2014
6	Lasers (Laser) 03/2023 - 09/2005
4	Photochemotherapy (Photodynamic Therapy) 11/2023 - 01/2021
4	Intravitreal Injections 10/2023 - 02/2006
3	Injections 01/2023 - 01/2017
3	Vitrectomy 02/2021 - 02/2014
3	Intraocular Injections 11/2006 - 09/2005
2	Topical Administration 06/2023 - 07/2008
2	Slit Lamp 01/2017 - 03/2014
1	Light Coagulation 03/2023
1	Intraocular Lenses (Intraocular Lens) 02/2023
1	Corneal Transplantation (Keratoplasty) 01/2023
1	Traction 02/2021
1	Contact Lenses 01/2021
1	Aftercare (After-Treatment) 01/2021